This volume contains letters (a few in shorthand) relating to his pursuit of the position as principal recorder, and then, upon accomplishing this, his problems in publishing. There are sales accounts and a diary (April, 1793 to June, 1794), written while he was imprisoned in Newgate Prison, London (1793 to Jan., 1796). Included for this period is an interesting description, brought to him at Newgate by an Englishman, John Ford, who was seeking support and American contacts for his plan to take an English textile process to America: "A Manufacture of Wollen & Cotton Cloth & Without spinning or weaving," August, 1794.

This collection includes notes and an unpublished manuscript (275 pages), entitled "Journals and Note-books of Benjamin Smith Barton, 1785-1806," by Waldo L. McAtee. The manuscript includes an introduction with biographical and bibliographical notes, an annotated glossary-index, and an indexed bibliography of works referred to in the various journals. The photocopies of journals and notebooks by Barton include his survey of the boundary of western Pennsylvania and Ohio, 1785; a commonplace book, 1789; journey through New York to Niagara Falls, 1797; Pennsylvania journal, 1798; visit to Virginia, 1802 (published); Salt Pond Mountain, Virginia, 1806; notes on vertebrates and miscellany.

The collection contains information on Fox family speculation in western lands, two manuscript maps from the 1790's and 1830's depicting the family's holdings in northwestern Pennsylvania, and a photograph album from the 1890's documenting Chestnutwold, the Fox estate adjacent to Andalusia. Chief correspondents are Samuel and George Fox.